Steroid receptor coregulator diversity: what can it mean for the stressed brain?

@article{Meijer2006SteroidRC,
  title={Steroid receptor coregulator diversity: what can it mean for the stressed brain?},
  author={Onno C. Meijer and Siem van der Laan and Servane B Lachize and P. J. Steenbergen and Edo Ronald de Kloet},
  journal={Neuroscience},
  year={2006},
  volume={138 3},
  pages={891-9}
}
Glucocorticoid hormones modulate brain function and as such are crucial for responding and adjusting to physical and psychological stressors. Their effects are mediated via mineralo- and glucocorticoid receptors, which in large measure act as transcription factors to modulate transcription of target genes, in a receptor-, cell-, and state-specific manner. The nature and magnitude of these transcriptional effects depend on the presence and activity of downstream proteins, such as steroid… CONTINUE READING

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