Steroid myopathy in connective tissue disease.

  title={Steroid myopathy in connective tissue disease.},
  author={Amir Abbas Askari and P J Vignos and Roland W. Moskowitz},
  journal={The American journal of medicine},
  volume={61 4},
In eight women with polymyositis (three patients), systemic lupus erythematosus (SLE) (three patients), rheumatoid arthritis (one patient) and shoulder-hand syndrome (one patient), weakness developed during high dose prednisone therapy. These women were studied using serial functional and manual muscle tests, determination of serum glutamic oxaloacetic transminase (SGOT), creatine phosphokinase (CPK) and serum aldolase levels, and urinary excretion of creatine. Insidious onset of weakness was… CONTINUE READING


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