Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism


BACKGROUND Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse metabolic risk in primary aldosteronism extends beyond hypertension, with increased rates of insulin resistance, type 2 diabetes, and osteoporosis, which cannot be easily explained by… (More)
DOI: 10.1172/jci.insight.93136


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@inproceedings{Arlt2017SteroidMA, title={Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism}, author={Wiebke Arlt and Katharina M H Lang and Alice J. Sitch and Anna Stephanie Dietz and Yara Rhayem and Irina Bancos and Annette Feuchtinger and Vasileios Chortis and Lorna C. Gilligan and Philippe Ludwig and Anna Riester and Evelyn Asbach and Beverly A. Hughes and Donna M. O’Neil and Martin Bidlingmaier and Jeremy W. Tomlinson and Zaki K. Hassan-Smith and D. Aled Rees and Christian Adolf and Stefanie Hahner and Marcus Quinkler and Tanja Dekkers and Jaap Deinum and Michael Biehl and Brian G Keevil and Cedric H. L. Shackleton and Jonathan J. Deeks and Axel Walch and Felix Beuschlein and Martin Reincke}, booktitle={JCI insight}, year={2017} }