Steroid metabolism and profile of steroidogenic gene expression in Episkin: high similarity with human epidermis.

@article{LuuThe2007SteroidMA,
  title={Steroid metabolism and profile of steroidogenic gene expression in Episkin: high similarity with human epidermis.},
  author={Van Luu-The and Corinne Ferraris and Daniel Duch{\'e} and Patrick B{\'e}langer and Jacques Leclaire and Fernand Labrie},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={2007},
  volume={107 1-2},
  pages={30-6}
}
The skin is a well-recognized site of steroid formation and metabolism. Episkin is a cultured human epidermis. In this report, we investigate whether Episkin possesses a steroidogenic machinery able to metabolize adrenal steroid precursors into active steroids. Episkin was incubated with [14C]-dehydroepiandrosterone (DHEA) and 4-androstenedione (4-dione… CONTINUE READING