Steroid hormone receptor status of mouse mammary stem cells.

  title={Steroid hormone receptor status of mouse mammary stem cells.},
  author={Marie-Liesse Asselin-Labat and Mark Shackleton and John Stingl and François Vaillant and Natasha C. Forrest and Connie J. Eaves and Jane E. Visvader and Geoffrey J Lindeman},
  journal={Journal of the National Cancer Institute},
  volume={98 14},
The estrogen receptor alpha (ERalpha), progesterone receptor (PR), and erbB2 (Her2 in humans) are important prognostic markers of human breast cancer, and they are variably expressed in different subtypes of breast cancer. The basal subtype, for example, is negative for ERalpha, PR, and Her2 by immunohistochemistry. We investigated the expression of these… CONTINUE READING