Steroid hormone receptor phosphorylation: is there a physiological role?

  title={Steroid hormone receptor phosphorylation: is there a physiological role?},
  author={George G. J. M. Kuiper and Albert O. Brinkmann},
  journal={Molecular and cellular endocrinology},
  volume={100 1-2},
All members of the steroid hormone receptor family are phosphoproteins. Additional phosphorylation occurs in the presence of hormone. This hormone-induced phosphorylation, which is 2- to 7-fold more than the basal phosphorylation, is a rapid process. All steroid receptors are phosphorylated at more than one single site. Most phosphorylation sites are located in the N-terminal domain, and phosphorylation occurs mainly on serine residues. Phosphorylation on threonine residues occurs in only a few… CONTINUE READING


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Trends Endocrinol

  • G. S. Takimoto, K. B. Horwitz
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  • 1993
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