Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model

@article{Norman2004SteroidhormoneRA,
  title={Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model},
  author={A. Norman and Mathew T. Mizwicki and Derek P. G. Norman},
  journal={Nature Reviews Drug Discovery},
  year={2004},
  volume={3},
  pages={27-41}
}
Steroid hormones can act as chemical messengers in a wide range of species and target tissues to produce both slow genomic responses, and rapid non-genomic responses. Although it is clear that genomic responses to steroid hormones are mediated by the formation of a complex of the hormone and its cognate steroid-hormone nuclear receptor, new evidence indicates that rapid responses are mediated by a variety of receptor types associated with the plasma membrane or its caveolae components… Expand
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