Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation.

@article{Giudice1992SteroidAP,
  title={Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation.},
  author={Linda C. Giudice and B A Dsupin and Juan C. Irwin},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1992},
  volume={75 5},
  pages={1235-41}
}
Endometrial stromal cells undergo decidual transformation, in response to epidermal growth factor (EGF) and progesterone. Since insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) are believed to be involved in endometrial differentiation, and insulin regulates IGFBP production in a variety of cells, we have investigated the modulatory roles of EGF, progesterone, and insulin on IGFBP secretion by long term cultures of human endometrial stromal cells. Without insulin, the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

IGF-1 and IGFBP-1 in peripheral blood and decidua of early miscarriages with euploid embryos: comparison between women with and without PCOS.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2016
View 1 Excerpt

Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2015
View 1 Excerpt

Similar Papers

Loading similar papers…