Steroid Receptor RNA Activator - A nuclear receptor coregulator with multiple partners: Insights and challenges.

  title={Steroid Receptor RNA Activator - A nuclear receptor coregulator with multiple partners: Insights and challenges.},
  author={Shane M. Colley and Peter J. Leedman},
  volume={93 11},
Steroid Receptor RNA Activator (SRA) occupies a unique and enigmatic position within the nuclear receptor (NR) field and more broadly in transcriptional regulation. This is as a result of its transcripts having both coding and non-coding coactivator activities along with its protein product SRAP performing mixed coactivator/repressor functions. Recent publications have provided greater understanding of SRA gene product activities and how they affect not only NR function, but now more broadly… CONTINUE READING


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