Steroid Hormones Use Non-Genomic Mechanisms to Control Brain Functions and Behaviors: A Review of Evidence

@article{Moore1999SteroidHU,
  title={Steroid Hormones Use Non-Genomic Mechanisms to Control Brain Functions and Behaviors: A Review of Evidence},
  author={Frank L. Moore and Simon J. Evans},
  journal={Brain, Behavior and Evolution},
  year={1999},
  volume={54},
  pages={41 - 50}
}
Progestins, estrogens, androgens, and corticosteroids are capable of modifying brain functions and behaviors by mechanisms that involve the classic genomic model for steroid action. However, experimental evidence indicates that some responses to steroid hormones use non-classical, non-genomic mechanisms. This paper reviews the evidence that steroids can bind to receptors in the plasma membrane, activate cell signaling pathways, and regulate responses on a time scale of seconds or a few minutes… 

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