Steroid-Associated Hip Joint Collapse in Bipedal Emus

  title={Steroid-Associated Hip Joint Collapse in Bipedal Emus},
  author={Li-zhen Zheng and Zhong Liu and Ming Lei and Jiang Peng and Yi-xin He and Xin-hui Xie and Chi-Wai Man and Le Huang and Xin-luan Wang and Daniel Tik-Pui Fong and De-ming Xiao and Da-ping Wang and Yang Chen and Jian Feng and Ying Liu and Ge Zhang and Ling Qin},
  booktitle={PloS one},
In this study we established a bipedal animal model of steroid-associated hip joint collapse in emus for testing potential treatment protocols to be developed for prevention of steroid-associated joint collapse in preclinical settings. Five adult male emus were treated with a steroid-associated osteonecrosis (SAON) induction protocol using combination of pulsed lipopolysaccharide (LPS) and methylprednisolone (MPS). Additional three emus were used as normal control. Post-induction, emu gait was… CONTINUE READING
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