Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster.

@article{Mrkus2005SterileWI,
  title={Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster.},
  author={R{\'o}bert M{\'a}rkus and {\'E}va Kurucz and Florentina Rus and Istv{\'a}n And{\'o}},
  journal={Immunology letters},
  year={2005},
  volume={101 1},
  pages={108-11}
}
An attack and oviposition by parasitic wasp Leptopilina boulardi induces a vigorous cellular immune response in Drosophila melanogaster larvae. This response is manifested by the appearance of a specialized subset of blood cells, the lamellocytes, which are the key players in the encapsulation and killing of the parasite. The formation of lamellocytes involves the activation of the Toll, the Jun kinase and the JAK/STAT pathways however the minimal requirement for initiation of lamellocyte… CONTINUE READING

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