Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ‐E) or type I interferon

@article{Tanaka2010SterileAM,
  title={Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ‐E) or type I interferon},
  author={Masahiko Tanaka and Takashi Shimbo and Yasushi Kikuchi and Masahide Matsuda and Yasufumi Kaneda},
  journal={International Journal of Cancer},
  year={2010},
  volume={126}
}
Malignant glioma is one of the most aggressive cancers. For the development of effective therapeutic strategies against such malignant diseases, elucidation of molecular targets is necessary. We found that inactivated Sendai virus particle (HVJ‐E) induced extensive cell death in the human glioblastoma cell line U251MG. Intradermal U251MG tumors were more effectively suppressed by HVJ‐E than interferon (IFN)‐β. From microarray analysis of gene expression in U251MG cells treated with HVJ‐E, we… 
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