Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.

@article{Aoyama2006StereotacticRP,
  title={Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.},
  author={Hidefumi Aoyama and Hiroki Shirato and M. Tago and Keiichi Nakagawa and Tatsuya Toyoda and Kazuo Hatano and Masahiro Kenjyo and Natsuo Oya and Saeko Hirota and Hiroki Shioura and Etsuo Kunieda and Taisuke Inomata and Kazushige Hayakawa and Norio Katoh and G. Kobashi},
  journal={JAMA},
  year={2006},
  volume={295 21},
  pages={2483-91}
}
CONTEXT In patients with brain metastases, it is unclear whether adding up-front whole-brain radiation therapy (WBRT) to stereotactic radiosurgery (SRS) has beneficial effects on mortality or neurologic function compared with SRS alone. OBJECTIVE To determine if WBRT combined with SRS results in improvements in survival, brain tumor control, functional preservation rate, and frequency of neurologic death. DESIGN, SETTING, AND PATIENTS Randomized controlled trial of 132 patients with 1 to 4… CONTINUE READING
Highly Influential
This paper has highly influenced 73 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 17 times over the past 90 days. VIEW TWEETS
598 Citations
24 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 598 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…