Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases

  title={Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases},
  author={Hany Soliman and Sunit Das and David A. Larson and Arjun Sahgal},
Stereotactic radiosurgery (SRS) is an established non-invasive ablative therapy for brain metastases. Early clinical trials with SRS proved that tumor control rates are superior to whole brain radiotherapy (WBRT) alone. As a result, WBRT plus SRS was widely adopted for patients with a limited number of brain metastases ("limited number" customarily means 1-4). Subsequent trials focused on answering whether WBRT upfront was necessary at all. Based on current randomized controlled trials (RCTs… CONTINUE READING
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