Stereotactic iodine-125 brachytherapy for treatment of inoperable focal brainstem gliomas of WHO grades I and II: feasibility and long-term outcome

@article{Ruge2012StereotacticIB,
  title={Stereotactic iodine-125 brachytherapy for treatment of inoperable focal brainstem gliomas of WHO grades I and II: feasibility and long-term outcome},
  author={Maximilian I Ruge and Philipp Kickingereder and Thorsten Simon and H Treuer and Volker J{\"o}rg Friedrich Sturm},
  journal={Journal of Neuro-Oncology},
  year={2012},
  volume={109},
  pages={273-283}
}
Microsurgical resection is the most frequently suggested treatment option for accessible focal brainstem gliomas (F-BSG) of World Health Organization (WHO) grades I and II. Because of their location in the highly eloquent brain, however, resection is associated with permanent postoperative morbidity, ranging from 12 to 33 %. Only a few reports have suggested stereotactic brachytherapy (SBT) with implantation of iodine-125 seeds as a local treatment alternative. Between 1993 and 2010, 47… CONTINUE READING
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