Organic Synthses; Wiley: New York, 1993; Collect
- J. Jacques, C. Fouquey
- Organic Synthses; Wiley: New York, 1993; Collect
High diastereoselectivity is observed in the preparation of configurationally stable allocolchicinoids 5 from Fischer carbene complexes 4 and 1-pentyne. The analogous reaction of complexes 8 gives 9 with moderate diastereoselectivity for the opposite atropisomer and this selectivity can be taken to high levels under thermodynamic conditions.