Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection.

@article{Heitz2019StereoselectivePR,
  title={Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection.},
  author={Mark P. Heitz and Sacha Javor and Tamis Darbre and Jean‐Louis Reymond},
  journal={Bioconjugate chemistry},
  year={2019}
}
Transfecting nucleic acids into cells is an essential procedure in biological research usually performed using nonviral transfection reagents. Unfortunately, most transfection reagents have polymeric or undisclosed structures and require nonstandard synthetic procedures. Herein we report peptide dendrimers accessible as pure products from standard building blocks by solid-phase peptide synthesis and acting as nontoxic single component siRNA transfection reagents for a variety of cell lines with… 

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