Stereoselective Analysis and Dissipation of Propiconazole in Wheat, Grapes, and Soil by Supercritical Fluid Chromatography-Tandem Mass Spectrometry.

Abstract

An efficient and sensitive chiral analytical method was established for the determination of propiconazole stereoisomers by supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS). Stereoisomeric separation was performed on a Chiralpak AD-3 column with CO2/ethanol (93:7) as the mobile phase. The four propiconazole stereoisomers were well separated in 4.7 min with resolutions above 2.0. The specificity, linearity, matrix effects, accuracy, precision, and stability of the developed method were evaluated. The stereoselective dissipation of propiconazole in wheat straw, grape, and soil samples was investigated according to the proposed method. The results indicated that significant stereoselective degradation occurred in wheat straw and grapes, with preferential degradation of (-)-propiconazole A and (+)-propiconazole B in wheat straw and the opposite case in grapes. No enantioselectivity was observed in soil, although diastereoisomer A degraded more rapidly than diastereoisomer B. These results could contribute to a more accurate assessment of the environmental risk and food safety of propiconazole.

DOI: 10.1021/acs.jafc.6b04623

Cite this paper

@article{Cheng2017StereoselectiveAA, title={Stereoselective Analysis and Dissipation of Propiconazole in Wheat, Grapes, and Soil by Supercritical Fluid Chromatography-Tandem Mass Spectrometry.}, author={Youpu Cheng and Yongquan Zheng and Fengshou Dong and Jing Li and Yaofang Zhang and Shuhong Sun and Ning Li and Xin Cui and Yuanhong Wang and Xinglu Pan and Weilong Zhang}, journal={Journal of agricultural and food chemistry}, year={2017}, volume={65 1}, pages={234-243} }