Stereoisomery and the release of the adrenergic neurotransmitter by indirectly acting sympathomimetics.

  • R Scivoletto
  • Published 1983 in
    Brazilian journal of medical and biological…


The isolated right rat atrium was used to investigate the chronotropic effects of dl-tranylcypromine and its d- and l-isomers. The concentration-effect curves of the three compounds were similar. The response of the preparation to the three drugs was completely blocked by pretreatment of the animal with reserpine, thus indicating an indirect effect of the… (More)