Stereoisomeric separation and toxicity of the nematicide fosthiazate.

  title={Stereoisomeric separation and toxicity of the nematicide fosthiazate.},
  author={Kunde Lin and Feng Zhang and Shanshan Zhou and Weiping Liu and Jay Gan and Zhiyan Pan},
  journal={Environmental toxicology and chemistry},
  volume={26 11},
Considerable attention has been paid to the enantiomeric resolution and toxicity of some chiral organophosphorous pesticides (OPs) with one asymmetric center, but research concerning chiral OPs with two asymmetric centers is still limited. In the present study, the stereoisomeric separation and toxicity of fosthiazate, a chiral OP with two asymmetric centers on phosphorus and carbon atoms, was investigated. All four stereoisomers of fosthiazate were separated successfully with a Chiralpak(R) AD… CONTINUE READING


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