Stereodivergent synthesis of enantioenriched 4-hydroxy-2-cyclopentenones.

@article{Singh2014StereodivergentSO,
  title={Stereodivergent synthesis of enantioenriched 4-hydroxy-2-cyclopentenones.},
  author={Gurpreet Singh and Angelica M Meyer and Jeffrey Aub{\'e}},
  journal={The Journal of organic chemistry},
  year={2014},
  volume={79 1},
  pages={452-8}
}
Protected 4-hydroxycyclopentenones (4-HCPs) constitute an important class of intermediates in chemical synthesis. A route to this class of compound has been developed. Key steps include Noyori reduction (which establishes the stereochemistry of the product), ring-closing metathesis, and simple functional group conversions to provide a set of substituted 4… CONTINUE READING