Stereocontrolled solution and solid phase enolate alkylations and hydroxylations — generation of three and four contiguous stereogenic carbon atoms in acyclic systems

@article{Hanessian1999StereocontrolledSA,
  title={Stereocontrolled solution and solid phase enolate alkylations and hydroxylations — generation of three and four contiguous stereogenic carbon atoms in acyclic systems},
  author={S. Hanessian and J. Ma and Wengui Wang},
  journal={Tetrahedron Letters},
  year={1999},
  volume={40},
  pages={4631-4634}
}
Abstract Potassium enolates of γ-alkoxy-α-methyl pentanoates can be alkylated with allylic and benzylic halides in solution and on solid phase with high 2,3- syn selectivity. Polypropionate units can be constructed on solid phase by a series of stereocontrolled conjugate additions and enolate hydroxylations relying on 1,2-induction. 
11 Citations
Organometallic chemistry on solid phase. An overview.
Tracelessness Unmasked: A General Linker Nomenclature.
The enterprise of synthesis: from concept to practice.
  • S. Hanessian
  • Chemistry, Medicine
  • The Journal of organic chemistry
  • 2012
Electrophile Cleavable Linker Units
...
1
2
...

References

SHOWING 1-10 OF 20 REFERENCES
...
1
2
...