Stereochemistry of mephedrone neuropharmacology: enantiomer-specific behavioural and neurochemical effects in rats.

@article{Gregg2015StereochemistryOM,
  title={Stereochemistry of mephedrone neuropharmacology: enantiomer-specific behavioural and neurochemical effects in rats.},
  author={Ryan A. Gregg and Michael Heinrich Baumann and John S. Partilla and Julie S Bonano and Alexandre G Vouga and Christopher S. Tallarida and Venkata Velvadapu and Garry R. Smith and Mary Melissa Peet and Allen B. Reitz and S. Stevens Negus and Scott Manning Rawls},
  journal={British journal of pharmacology},
  year={2015},
  volume={172 3},
  pages={883-94}
}
BACKGROUND AND PURPOSE Synthetic cathinones, commonly referred to as 'bath salts', are a group of amphetamine-like drugs gaining popularity worldwide. 4-Methylmethcathinone (mephedrone, MEPH) is the most commonly abused synthetic cathinone in the UK, and exerts its effects by acting as a substrate-type releaser at monoamine transporters. Similar to other cathinone-related compounds, MEPH has a chiral centre and exists stably as two enantiomers: R-mephedrone (R-MEPH) and S-mephedrone (S-MEPH… CONTINUE READING
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