Stepwise multiphoton activation fluorescence reveals a new method of melanin detection.

  title={Stepwise multiphoton activation fluorescence reveals a new method of melanin detection.},
  author={Zhenhua Lai and Josef Kerimo and Yair Mega and Charles A. DiMarzio},
  journal={Journal of biomedical optics},
  volume={18 6},
The stepwise multiphoton activated fluorescence (SMPAF) of melanin, activated by a continuous-wave mode near infrared (NIR) laser, reveals a broad spectrum extending from the visible spectra to the NIR and has potential application for a low-cost, reliable method of detecting melanin. SMPAF images of melanin in mouse hair and skin are compared with conventional multiphoton fluorescence microscopy and confocal reflectance microscopy (CRM). By combining CRM with SMPAF, we can locate melanin… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 26 references

Melanin fluorescence spectra by step - wise three photon activation

  • J. Kerimo Lai, C. A. DiMarzio
  • Photochem . Photobiol .
  • 2011

Warrena, “Estimation of molar absorptivities and pigment sizes for eumelanin and pheomelanin using femtosecond transient absorption spectroscopy,

  • I. Piletic, T. Matthews
  • J. Chem. Phys. 131(18),
  • 2009
1 Excerpt

new method for noninvasive skin investigation and melanoma detection,” J

  • G. Zonios et al., “Melanin absorption spectroscopy
  • Biomed. Opt. 13(1), 014017
  • 2008

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