Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration.

@article{Ohlemacher2016StepwiseDO,
  title={Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration.},
  author={Sarah K. Ohlemacher and Akshayalakshmi Sridhar and Yucheng Xiao and Alexandra E Hochstetler and Mansoor Sarfarazi and Theodore R. Cummins and Jason S. Meyer},
  journal={Stem cells},
  year={2016},
  volume={34 6},
  pages={1553-62}
}
Human pluripotent stem cells (hPSCs), including both embryonic and induced pluripotent stem cells, possess the unique ability to readily differentiate into any cell type of the body, including cells of the retina. Although previous studies have demonstrated the ability to differentiate hPSCs to a retinal lineage, the ability to derive retinal ganglion cells (RGCs) from hPSCs has been complicated by the lack of specific markers with which to identify these cells from a pluripotent source. In the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 26 times over the past 90 days. VIEW TWEETS
12 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…