Step training reinforces specific spinal locomotor circuitry in adult spinal rats.

@article{Ichiyama2008StepTR,
  title={Step training reinforces specific spinal locomotor circuitry in adult spinal rats.},
  author={Ronaldo M Ichiyama and Gr{\'e}goire Courtine and Yury P. Gerasimenko and Grace J Yang and Rubia van den Brand and Igor Aleksandrovich Lavrov and Hui Zhong and Roland R. Roy and V. Reggie Edgerton},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2008},
  volume={28 29},
  pages={7370-5}
}
Locomotor training improves function after a spinal cord injury both in experimental and clinical settings. The activity-dependent mechanisms underlying such improvement, however, are sparsely understood. Adult rats received a complete spinal cord transection (T9), and epidural stimulation (ES) electrodes were secured to the dura matter at L2. EMG electrodes were implanted bilaterally in selected muscles. Using a servo-controlled body weight support system for bipedal stepping, five rats were… CONTINUE READING