Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.

@article{Srikanth2014StemCO,
  title={Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.},
  author={Priya Srikanth and Tracy L Young-Pearse},
  journal={Journal of neurogenetics},
  year={2014},
  volume={28 1-2},
  pages={5-29}
}
Seven years have passed since the initial report of the generation of induced pluripotent stem cells (iPSCs) from adult human somatic cells, and in the intervening time the field of neuroscience has developed numerous disease models using this technology. Here, we review progress in the field and describe both the advantages and potential pitfalls of modeling neurodegenerative and neurodevelopmental diseases using this technology. We include tables with information on neural differentiation… CONTINUE READING
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