Stem cells of the respiratory system: from identification to differentiation into functional epithelium.

@article{Green2013StemCO,
  title={Stem cells of the respiratory system: from identification to differentiation into functional epithelium.},
  author={Michael Green and Sarah X L Huang and H. -W. Snoeck},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2013},
  volume={35 3},
  pages={261-70}
}
We review recent progress in the stem cell biology of the respiratory system, and discuss its scientific and translational ramifications. Several studies have defined novel stem cells in postnatal lung and airways and implicated their roles in tissue homeostasis and repair. In addition, significant advances in the generation of respiratory epithelium from pluripotent stem cells (PSCs) now provide a novel and powerful platform for understanding lung development, modeling pulmonary diseases, and… CONTINUE READING