Stem cells in human neurodegenerative disorders--time for clinical translation?

@article{Lindvall2010StemCI,
  title={Stem cells in human neurodegenerative disorders--time for clinical translation?},
  author={Olle Lindvall and Zaal Kokaia},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 1},
  pages={29-40}
}
Stem cell-based approaches have received much hype as potential treatments for neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in animal models of neurodegenerative diseases can improve function by replacing the lost neurons and glial cells and by mediating remyelination, trophic actions, and modulation of inflammation. Endogenous neural stem cells are also potential therapeutic targets because they produce neurons and glial cells in response to injury… CONTINUE READING