Stem cells in development of therapeutics for Parkinson's disease: a perspective.

@article{Xi2008StemCI,
  title={Stem cells in development of therapeutics for Parkinson's disease: a perspective.},
  author={Jiajie Xi and Su-chun Zhang},
  journal={Journal of cellular biochemistry},
  year={2008},
  volume={105 5},
  pages={1153-60}
}
Using Parkinson's disease as a prototype of neurodegenerative diseases, we propose applications of human stem cells in the development of therapeutics for neurodegenerative diseases. First, in vitro differentiation of human stem cells offers a versatile model for dissecting molecular interactions underlying human dopamine (DA) neuron specification, which may form a foundation for instigating regeneration of DA neurons from progenitors that reside in the brain. Second, stem cells derived from… CONTINUE READING