Stem cells in brain tumor development.

  title={Stem cells in brain tumor development.},
  author={Sheila R. Alcantara Llaguno and Yuntao Chen and Ren{\'e}e M. McKay and Luis F. Parada},
  journal={Current topics in developmental biology},
Gliomas are highly infiltrative and aggressive brain tumors that are resistant to conventional therapies. Recent studies have implicated neural stem cells (NSCs) in brain tumor initiation and development. Subpopulations of stem-like cancer cells have also been isolated from brain tumors, and are purported to be important mediators of malignant behavior and… CONTINUE READING