Stem cells from human exfoliated deciduous tooth-derived conditioned medium enhance recovery of focal cerebral ischemia in rats.

@article{Inoue2013StemCF,
  title={Stem cells from human exfoliated deciduous tooth-derived conditioned medium enhance recovery of focal cerebral ischemia in rats.},
  author={Takanori Inoue and Masahiko Sugiyama and Hisashi Hattori and Hideaki Wakita and Toshihiko Wakabayashi and Minoru Ueda},
  journal={Tissue engineering. Part A},
  year={2013},
  volume={19 1-2},
  pages={24-9}
}
Regenerative therapy using stem cells is a promising approach for the treatment of stroke. Recently, we reported that dental pulp stem cells (DPSC) ameliorated ischemic tissue injury in the rat brain and accelerated functional recovery after middle cerebral artery occlusion (MCAO). In this study, we investigated the effects of stem cells from human exfoliated deciduous tooth (SHED)-derived conditioned medium (SHED-CM) on permanent MCAO (pMCAO). Adult male Sprague-Dawley rats were subjected to… CONTINUE READING

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