Stem cells as source for retinal pigment epithelium transplantation.

  title={Stem cells as source for retinal pigment epithelium transplantation.},
  author={Evelina Bertolotti and Alberto Neri and Monica Camparini and Claudio Macaluso and Valeria Marigo},
  journal={Progress in retinal and eye research},
Inherited maculopathies, age related macular degeneration and some forms of retinitis pigmentosa are associated with impaired function or loss of the retinal pigment epithelium (RPE). Among potential treatments, transplantation approaches are particularly promising. The arrangement of RPE cells in a well-defined tissue layer makes the RPE amenable to cell or tissue sheet transplantation. Different cell sources have been suggested for RPE transplantation but the development of a clinical… CONTINUE READING