Stem cells: hype and reality.

  title={Stem cells: hype and reality.},
  author={Catherine M. Verfaillie and Martin F Pera and Peter M. Lansdorp},
  journal={Hematology. American Society of Hematology. Education Program},
This update discusses what is known regarding embryonic and adult tissue-derived pluripotent stem cells, including the mechanisms underlying self-renewal without senescence, differentiation in multiple cell types both in vitro and in vivo, and future potential clinical uses of such stem cells. In Section I, Dr. Lansdorp reviews the structure and function of telomerase, the enzyme that restores telomeric ends of chromosomes upon cell division, highly present in embryonic stem cells but not adult… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 55 extracted citations

G Protein-Coupled Receptor Signaling in Stem Cells and Cancer

International journal of molecular sciences • 2016
View 10 Excerpts
Highly Influenced

Cell-replacement therapy with stem cells in neurodegenerative diseases.

Current neurovascular research • 2004
View 4 Excerpts
Highly Influenced

Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 2017
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 156 references

Stem cell transplantation in the fetus.

Cancer control : journal of the Moffitt Cancer Center • 2004

Endothelial cells derived from human embryonic stem cells.

Proceedings of the National Academy of Sciences of the United States of America • 2002

Similar Papers

Loading similar papers…