Stem cells: hype and reality.

@article{Verfaillie2002StemCH,
  title={Stem cells: hype and reality.},
  author={Catherine M. Verfaillie and Martin F Pera and Peter M. Lansdorp},
  journal={Hematology. American Society of Hematology. Education Program},
  year={2002},
  pages={369-91}
}
This update discusses what is known regarding embryonic and adult tissue-derived pluripotent stem cells, including the mechanisms underlying self-renewal without senescence, differentiation in multiple cell types both in vitro and in vivo, and future potential clinical uses of such stem cells. In Section I, Dr. Lansdorp reviews the structure and function of telomerase, the enzyme that restores telomeric ends of chromosomes upon cell division, highly present in embryonic stem cells but not adult… CONTINUE READING

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