Stem cells, microenvironment mechanics, and growth factor activation.

Abstract

Physicochemical features of a cell's microenvironment can exert important effects on cell behavior and include the effects of matrix elasticity on cell differentiation processes, but molecular mechanisms are largely mysterious. Here we highlight recent reports of a mechanical dependence to growth factor activation, with a particular focus on release of… (More)
DOI: 10.1016/j.ceb.2009.06.003

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