Stem cell transplantation for chronic lymphocytic leukemia: should not more patients get a transplant?

@article{Jabbour2004StemCT,
  title={Stem cell transplantation for chronic lymphocytic leukemia: should not more patients get a transplant?},
  author={Elias J Jabbour and Michael J Keating and Richard E. Champlin and Issa F. Khouri},
  journal={Bone Marrow Transplantation},
  year={2004},
  volume={34},
  pages={289-297}
}
Summary:Novel therapeutic approaches with conventional chemotherapy and monoclonal antibody combinations have improved the complete remission rates in chronic lymphocytic leukemia. However, cure remains elusive, particularly in fludarabine-refractory patients, whose prognosis remains poor. Autologous stem cell transplantation (SCT) has been explored for such patients, lengthening the time to treatment failure in selected patients, but there is little hope that it will improve the cure rate. The… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 72 references

Allogeneic, but not autologous, stem-cell transplantation overcomes the negative impact of unmutated VH genes in patients with CLL

  • C Moreno, D Colomer, N Villamor
  • Blood
  • 2003

Can Zap-70 protein expression in b-CLL as detected by immunohistochemistry predict VH mutation status? Blood

  • SJM O’Conner, J Starczynski, J Teasdale
  • 2003

Can Zap70 protein expression in bCLL as detected by immunohistochemistry predict VH mutation status ?

  • J Starczynski, J Teasdale
  • Blood
  • 2003

Expression of ZAP-70 in both unmutated and mutated leukemic CLL B cells indicates lack of efficacy as a surrogate marker for immunoglobulin mutational status

  • BT Pittner, RC Tschumper, TK Kimlinger
  • Blood
  • 2003

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