Stem cell transplantation: past, present and future.

  title={Stem cell transplantation: past, present and future.},
  author={E. Donnall Thomas},
  journal={Archivum immunologiae et therapiae experimentalis},
  volume={45 1},
The early attempts at human allogeneic marrow transplants in the 1950's and 1960's were largely unsuccessful. The probability of success has improved steadily in the past two decades. Cure rates now range from 90% for non-malignant diseases transplanted early to 15% for patients with advanced leukemia. Most marrow transplants have involved an HLA matched sibling donor but, more recently, a matched unrelated volunteer marrow donor can be found for many patients without a family donor. Current… CONTINUE READING
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