Stem cell therapies for the treatment of radiation-induced normal tissue side effects.

@article{Benderitter2014StemCT,
  title={Stem cell therapies for the treatment of radiation-induced normal tissue side effects.},
  author={Marc Benderitter and Fabio Caviggioli and Alain A Chapel and Rob P Coppes and Chandan Guha and Marco Klinger and Olivier Malard and Fiona Stewart and Radia Tamarat and Peter van Luijk and Charles L. Limoli},
  journal={Antioxidants & redox signaling},
  year={2014},
  volume={21 2},
  pages={
          338-55
        }
}
SIGNIFICANCE Targeted irradiation is an effective cancer therapy but damage inflicted to normal tissues surrounding the tumor may cause severe complications. While certain pharmacologic strategies can temper the adverse effects of irradiation, stem cell therapies provide unique opportunities for restoring functionality to the irradiated tissue bed. RECENT ADVANCES Preclinical studies presented in this review provide encouraging proof of concept regarding the therapeutic potential of stem… CONTINUE READING

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