Stem cell-related markers in primary breast cancers and associated metastatic lesions

@inproceedings{Guler2012StemCM,
  title={Stem cell-related markers in primary breast cancers and associated metastatic lesions},
  author={Gulnur Guler and Serdar Balci and Stefan Costinean and Cigdem Himmetoglu Ussakli and Çiğdem Irkkan and Dinc Suren and Ebru Sari and Kadri Altundag and Yavuz Ozişik and Susie Jones and Jason Bacher and Charles L. Shapiro and Kay F Huebner},
  booktitle={Modern Pathology},
  year={2012}
}
It has been reported previously that: (1) normal-breast epithelial cells that are CD24−/44+ express higher levels of stem/progenitor cell-associated genes; (2) cancer cells that have undergone epithelial to mesenchymal transition display CD24−/44+ cell-surface expression, a marker for breast cancer stem cells; (3) loss of E-cadherin is a preliminary step in… CONTINUE READING