Stem cell mobilization induced by subcutaneous granulocyte-colony stimulating factor to improve cardiac regeneration after acute ST-elevation myocardial infarction: result of the double-blind, randomized, placebo-controlled stem cells in myocardial infarction (STEMMI) trial.

@article{Ripa2006StemCM,
  title={Stem cell mobilization induced by subcutaneous granulocyte-colony stimulating factor to improve cardiac regeneration after acute ST-elevation myocardial infarction: result of the double-blind, randomized, placebo-controlled stem cells in myocardial infarction (STEMMI) trial.},
  author={Rasmus Sejersten Ripa and Erik J\orgensen and Yong-zhong Wang and Jens Jakob Thune and Jens Christian Nilsson and L. G. S\ondergaard and Hans Erik Johnsen and Lars Valeur K\ober and P. Grande and Jens Kastrup},
  journal={Circulation},
  year={2006},
  volume={113 16},
  pages={1983-92}
}
BACKGROUND Phase 1 clinical trials of granulocyte-colony stimulating factor (G-CSF) treatment after myocardial infarction have indicated that G-CSF treatment is safe and may improve left ventricular function. This randomized, double-blind, placebo-controlled trial aimed to assess the efficacy of subcutaneous G-CSF injections on left ventricular function in patients with ST-elevation myocardial infarction. METHODS AND RESULTS Seventy-eight patients (62 men; average age, 56 years) with ST… CONTINUE READING
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