Stem cell fate dictated solely by altered nanotube dimension.


Two important goals in stem cell research are to control the cell proliferation without differentiation and to direct the differentiation into a specific cell lineage when desired. Here, we demonstrate such paths by controlling only the nanotopography of culture substrates. Altering the dimensions of nanotubular-shaped titanium oxide surface structures… (More)
DOI: 10.1073/pnas.0813200106


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