Stem cell factor induces phosphorylation of a 200 kDa protein which associates with c-kit.

@article{Linnekin1995StemCF,
  title={Stem cell factor induces phosphorylation of a 200 kDa protein which associates with c-kit.},
  author={Diana Linnekin and Jonathan R. Keller and Douglas K. Ferris and Susan M. Mou and Virginia C. Broudy and Dan L. Longo},
  journal={Growth factors},
  year={1995},
  volume={12 1},
  pages={57-67}
}
Stem cell factor (SCF) promotes limited proliferation and differentiation of hematopoietic progenitor cells and is potently synergistic in combination with growth factors such as granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin 3 (IL-3) or erythropoietin (Epo). We have examined tyrosine phosphorylation induced by SCF in the megakaryoblastic cell line Mo7e and found phosphorylation of proteins of 200, 145, 120, 58 and 55 kDa. The dominant phosphotyrosylproteins in SCF… CONTINUE READING