Stem-cell challenges in the treatment of Alzheimer's disease: a long way from bench to bedside.

  title={Stem-cell challenges in the treatment of Alzheimer's disease: a long way from bench to bedside.},
  author={Xiaotang Fan and Dayu Sun and Xiaotong Tang and Yulong Cai and Zheng Qin Yin and Haiwei Xu},
  journal={Medicinal research reviews},
  volume={34 5},
Alzheimer's disease (AD) is the most prevalent type of dementia, and its neuropathology is characterized by deposition of insoluble β-amyloid peptides, intracellular neurofibrillary tangles, and the loss of diverse neurons. Current pharmacological treatments for AD relieve symptoms without affecting the major pathological characteristics of the disease. Therefore, it is essential to develop new and effective therapies. Stem-cell types include tissue-specific stem cells, such as neural stem… CONTINUE READING


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