Stem and progenitor cell–based therapy of the human central nervous system

  title={Stem and progenitor cell–based therapy of the human central nervous system},
  author={Steve Goldman},
  journal={Nature Biotechnology},
Multipotent neural stem cells, capable of giving rise to both neurons and glia, line the cerebral ventricles of all adult animals, including humans. In addition, distinct populations of nominally glial progenitor cells, which also have the capacity to generate several cell types, are dispersed throughout the subcortical white matter and cortex. A number of approaches have evolved for using neural progenitor cells in cell therapy. Four strategies are especially attractive for clinical… CONTINUE READING


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