Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults.

@article{Capitano2004SteadystateIC,
  title={Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults.},
  author={Blair Capitano and Holly M Mattoes and Eric Shore and Aidan O'brien and Sidney S Braman and Chistina Sutherland and David P Nicolau},
  journal={Chest},
  year={2004},
  volume={125 3},
  pages={965-73}
}
STUDY OBJECTIVE To determine the steady-state, extracellular, and intracellular pulmonary disposition of moxifloxacin (MXF), levofloxacin (LEVO), and azithromycin (AZI) relative to that of the plasma over a 24-h dosing interval. DESIGN Randomized, multicenter, open-label investigation. PATIENTS Forty-seven older adults (mean [+/- SD] age, 62 +/- 13 years) undergoing diagnostic bronchoscopy. INTERVENTIONS Oral administration of MXF, 400 mg, LEVO, 500 mg daily for five doses, or AZI, 500 mg… CONTINUE READING

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Surveil - lance of resistance in bacteria causing community - acquired respiratory tract infection

D Felmingham, C Feldman, W Hryniewics
Clin Microbiol Infect • 2002

Surveillance of resistance in bacteria causing community-acquired respiratory tract infections.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases • 2002

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