Steady-state concentration of cyclosporin G (OG37-325) and its metabolites in renal transplant recipients.

Abstract

The steady-state concentrations of cyclosporin G (OG37-325) (CsG) and six of its metabolites (GM1, GM9, GM4N, GM1c, GM1c9, GM19) were measured throughout the 12-h dosing interval in six renal transplant recipients receiving CsG as prophylaxis against acute cellular rejection. The mean 12-h whole-blood trough concentrations (micrograms/L) were CsG, 131… (More)

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@article{Langman1994SteadystateCO, title={Steady-state concentration of cyclosporin G (OG37-325) and its metabolites in renal transplant recipients.}, author={Loralie J. Langman and Alan Leichtman and W. F. Weitzel and R. W. Yatscoff}, journal={Clinical chemistry}, year={1994}, volume={40 4}, pages={613-6} }