Staurosporine restores GTPgammaS induced block of rapid endocytosis in chromaffin cells.

Fast capacitance measurements demonstrated that chromaffin cells retrieve membrane by several kinetically different pathways. Here, we show that rapid endocytosis is blocked and slow endocytosis reduced by intracellular application of GTPgammaS, an activator of G-proteins, but not by the competitive blocker GDPbetaS. The inhibition of rapid endocytosis by… CONTINUE READING