Stats: Transcriptional Control and Biological Impact

  title={Stats: Transcriptional Control and Biological Impact},
  author={David E. Levy},
tion of the STAT proteins, named after their dual role as signal transducers and activators of transcription. These transcription factors are latent in the cytoplasm until they are activated by extracellular signalling proteins (mainly cytokines and growth factors, but also some peptides) that bind to specific cell-surface receptors. These extracellular-signalling proteins can activate various tyrosine kinases in the cell that phosphorylate STAT proteins. The activated STAT proteins accumulate… CONTINUE READING
Highly Influential
This paper has highly influenced 62 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
1,075 Citations
157 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 1,075 extracted citations


Publications referenced by this paper.
Showing 1-10 of 157 references

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IRF regulatory factor-1

  • Wong, H L.
  • J. Biol
  • 2002

Similar Papers

Loading similar papers…