Stats: Transcriptional Control and Biological Impact

@inproceedings{Levy2002StatsTC,
  title={Stats: Transcriptional Control and Biological Impact},
  author={David E. Levy},
  year={2002}
}
tion of the STAT proteins, named after their dual role as signal transducers and activators of transcription. These transcription factors are latent in the cytoplasm until they are activated by extracellular signalling proteins (mainly cytokines and growth factors, but also some peptides) that bind to specific cell-surface receptors. These extracellular-signalling proteins can activate various tyrosine kinases in the cell that phosphorylate STAT proteins. The activated STAT proteins accumulate… CONTINUE READING
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Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IRF regulatory factor-1

  • Wong, H L.
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  • 2002

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