Statistics of deformations in histology and application to improved alignment with MRI

@article{Schormann1995StatisticsOD,
  title={Statistics of deformations in histology and application to improved alignment with MRI},
  author={Thorsten Schormann and Andreas Dabringhaus and Karl Zilles},
  journal={IEEE transactions on medical imaging},
  year={1995},
  volume={14 1},
  pages={25-35}
}
An exact registration of magnetic resonance images (MRI) with histological sections is impeded by local deformations resulting from histological preparation procedures. Therefore, it is desirable to know the probability density function of spatial deformations in order to estimate optimal global least-square transformation parameters from suitable landmarks. For this reason, the statistics of deformations is investigated. It is shown analytically that the frequency of occurrence of the absolute… CONTINUE READING